The Department of Health is urging the public to remain vigilant for Mpox symptoms following a rapid increase in laboratory-confirmed cases across the country in recent weeks.
The department has recorded 18 confirmed cases and one probable case, warning that immediate and sustained public cooperation is needed to contain the spread.
“The majority, 15, of these cases were reported in the Western Cape, particularly in the City of Cape Town. Three were recorded in Gauteng and one in KwaZulu-Natal.
“Of concern is that 13 of the total cases were recorded between 13 August and 17 September, which suggests rapid local transmission of this preventable viral infection.
“All cases range in age from 23 to 50 years, with a median age of 36.5 years. Eighteen are male, with only one female,” said department spokesperson Foster Mohale.
Mohale said one of the most recent cases involved an individual who travelled to Spain earlier this month and returned to South Africa on 14 September.
“This person underwent testing in Spain after being informed of his probable case status.
“South African health authorities are in contact with their Spanish counterparts regarding the laboratory test results of the individual to confirm his Mpox status,” Mohale added.
Mpox can affect anyone who has been in close contact with someone who has tested positive for the virus, with symptoms potentially developing within 21 days of exposure.
The department stressed that continued surveillance, early detection and public cooperation are essential to preventing further transmission.
Mpox is a viral disease that can affect anyone, regardless of race, gender, sexual orientation or socioeconomic status.
The infection can cause a painful rash, swollen lymph nodes and flu-like symptoms. Other symptoms include fever, headache, muscle aches, back pain, fatigue, and rashes or skin lesions that may appear on the face, hands, feet, genitals or other parts of the body.
“Therefore, anyone experiencing these symptoms, particularly if they have had close contact with a confirmed or suspected case, should seek medical attention immediately and avoid close contact with others,” Mohale urged.


